Page 148 of 202 FirstFirst ... 4898138146147148149150158198 ... LastLast
Results 1,471 to 1,480 of 2017

Thread: Full Y Chromosome Sequencing: Phase III Pilot

  1. #1471
    Registered Users
    Posts
    15
    Sex

    posting error . . . .
    Last edited by drabcon; 03-15-2016 at 12:32 AM.
    ____________________________
    Brad

  2. #1472
    Company Rep Account
    Posts
    1,009
    Sex
    Y-DNA (P)
    R1b U106 Z81

    Quote Originally Posted by FGC Corp View Post
    Sale:

    30x whole genome: $1475.
    Now regular price will be $1475.
    FGC team member.

    Hidden Content

    Join our FGC google group:
    Hidden Content

    R1b-U106 google group:
    Forum for discussion of R1b-U106
    Discussion related to all products by any company will be welcome. Discussion will not be limited to FGC

    Join here:
    Hidden Content

  3. The Following User Says Thank You to FGC Corp For This Useful Post:

     gotten (03-15-2016)

  4. #1473
    Junior Member
    Posts
    2
    Sex

    How did the QC on your latest Y-Elite 2.1 turn out - was it as you hoped for?

  5. #1474
    Company Rep Account
    Posts
    1,009
    Sex
    Y-DNA (P)
    R1b U106 Z81

    Quote Originally Posted by JerryB View Post
    How did the QC on your latest Y-Elite 2.1 turn out - was it as you hoped for?
    That is still on-going.
    FGC team member.

    Hidden Content

    Join our FGC google group:
    Hidden Content

    R1b-U106 google group:
    Forum for discussion of R1b-U106
    Discussion related to all products by any company will be welcome. Discussion will not be limited to FGC

    Join here:
    Hidden Content

  6. #1475
    Company Rep Account
    Posts
    1,009
    Sex
    Y-DNA (P)
    R1b U106 Z81

    Quote Originally Posted by FGC Corp View Post
    Batch 9007 has been sequenced. Our analysis of the data will take about 15 days.
    Preliminary analysis suggests that Batch 9007 is the best of Y Elite 2.0 batches thus far. In terms of the CallableLoci metric, the data is better thus far than any Y Elite 1.0 batch we had.

    After a great deal of frustration getting this batch finished, this is a satisfying outcome.
    Last edited by FGC Corp; 03-18-2016 at 01:08 AM.
    FGC team member.

    Hidden Content

    Join our FGC google group:
    Hidden Content

    R1b-U106 google group:
    Forum for discussion of R1b-U106
    Discussion related to all products by any company will be welcome. Discussion will not be limited to FGC

    Join here:
    Hidden Content

  7. The Following 6 Users Say Thank You to FGC Corp For This Useful Post:

     bfcockburn (03-18-2016),  ChrisR (03-18-2016),  gotten (03-17-2016),  haleaton (03-18-2016),  MitchellSince1893 (03-18-2016),  morrisondna (03-18-2016)

  8. #1476
    Company Rep Account
    Posts
    1,009
    Sex
    Y-DNA (P)
    R1b U106 Z81

    Our average callable loci thus far is 14.8 million bases. Y Elite 1.0 was 14 million bases by comparison. Quality control of the Y Elite 2.1 data is currently underway.
    FGC team member.

    Hidden Content

    Join our FGC google group:
    Hidden Content

    R1b-U106 google group:
    Forum for discussion of R1b-U106
    Discussion related to all products by any company will be welcome. Discussion will not be limited to FGC

    Join here:
    Hidden Content

  9. The Following 4 Users Say Thank You to FGC Corp For This Useful Post:

     bfcockburn (03-19-2016),  gotten (03-19-2016),  MitchellSince1893 (03-19-2016),  VinceT (03-19-2016)

  10. #1477
    Junior Member
    Posts
    5
    Sex
    Location
    Edmonton, Canada
    Ethnicity
    Scottish, English, Jewish
    Nationality
    Canadian
    Y-DNA (P)
    R1b-U106/Z18/L257
    mtDNA (M)
    H5s

    Scotland England Ukraine Poland
    If I understand things properly, the sequenced 250-bp-long short reads in batch 9007 are being mapped to the hg37 reference genome. I would think that it would be interesting to see how the calls change when you map the same sequenced short read dataset to both hg37 and hg38, especially given the longer reads from Y Elite 2.0. What are the anticipated advantages, if any, to using hg38 over hg37 as far as detecting mutations in the Y chromosome? Is the genetic genealogy community inevitably going to move to hg38 because of clear advantages over hg37?

  11. The Following User Says Thank You to bfcockburn For This Useful Post:

     rod (03-19-2016)

  12. #1478
    Company Rep Account
    Posts
    1,009
    Sex
    Y-DNA (P)
    R1b U106 Z81

    Quote Originally Posted by bfcockburn View Post
    If I understand things properly, the sequenced 250-bp-long short reads in batch 9007 are being mapped to the hg37 reference genome. I would think that it would be interesting to see how the calls change when you map the same sequenced short read dataset to both hg37 and hg38, especially given the longer reads from Y Elite 2.0. What are the anticipated advantages, if any, to using hg38 over hg37 as far as detecting mutations in the Y chromosome? Is the genetic genealogy community inevitably going to move to hg38 because of clear advantages over hg37?
    Yes, there are advantages to hg38. James Kane discusses them here:
    http://www.it2kane.org/2015/11/ngs-y...ent-on-grch38/
    FGC team member.

    Hidden Content

    Join our FGC google group:
    Hidden Content

    R1b-U106 google group:
    Forum for discussion of R1b-U106
    Discussion related to all products by any company will be welcome. Discussion will not be limited to FGC

    Join here:
    Hidden Content

  13. The Following 2 Users Say Thank You to FGC Corp For This Useful Post:

     bfcockburn (03-20-2016),  JerryB (03-20-2016)

  14. #1479
    Junior Member
    Posts
    2
    Sex

    Thanks for the reference - I wasn't familiar with James Kane's work. Found interesting comparison on his website, definitely slanting to the positives of FGC. Although his comparison was Big Y to Y Elite 1.0 (lacking enough 2.0 - now 2.1 results to reference that testing), definitely shows the cost/coverage differential in your favor. http://www.it2kane.org/2015/11/which-ngs-test-to-take/

  15. #1480
    Company Rep Account
    Posts
    1,009
    Sex
    Y-DNA (P)
    R1b U106 Z81

    Quote Originally Posted by JerryB View Post
    Thanks for the reference - I wasn't familiar with James Kane's work. Found interesting comparison on his website, definitely slanting to the positives of FGC. Although his comparison was Big Y to Y Elite 1.0 (lacking enough 2.0 - now 2.1 results to reference that testing), definitely shows the cost/coverage differential in your favor. http://www.it2kane.org/2015/11/which-ngs-test-to-take/
    Note that there is a certain amount of variability in those numbers. Occasionally samples have somewhat less coverage (perhaps 90% of the mean) because of higher levels of bacteria in that individual's sample. That's why it is important to follow the instructions carefully in the sample collection process to mitigate bacterial contamination.
    Last edited by FGC Corp; 03-20-2016 at 05:02 PM.
    FGC team member.

    Hidden Content

    Join our FGC google group:
    Hidden Content

    R1b-U106 google group:
    Forum for discussion of R1b-U106
    Discussion related to all products by any company will be welcome. Discussion will not be limited to FGC

    Join here:
    Hidden Content

  16. The Following User Says Thank You to FGC Corp For This Useful Post:

     gotten (03-20-2016)

Page 148 of 202 FirstFirst ... 4898138146147148149150158198 ... LastLast

Similar Threads

  1. Replies: 12
    Last Post: 04-22-2018, 10:32 AM
  2. Replies: 39
    Last Post: 03-11-2018, 06:49 PM
  3. Replies: 254
    Last Post: 12-09-2014, 08:21 PM
  4. Full Y Chromosome Sequencing: Phase III Pilot
    By warwick in forum X Chromosome (X-DNA)
    Replies: 884
    Last Post: 10-07-2014, 11:56 PM
  5. Replies: 11
    Last Post: 08-15-2014, 02:06 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •