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Thread: Full Y Chromosome Sequencing: Phase III Pilot

  1. #1
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    Full Y Chromosome Sequencing: Phase III Pilot

    Hello,

    I'm doing a Phase III pilot of our Y Chromosome sequencing via my organization, Full Genomes, Inc. (Per the prior approval of admins I'm announcing it here). We can take a limited number of additional orders as we get going:

    You receive:

    1. Full Y chromosome sequence
    2. 400-600 STRs
    3. 9000 snps
    4. 14 gigabytes of data
    5. the full mtdna sequence can also be produced though we are doing quality control on this in the beta phase

    Cost: (not cheap) $1250 raw data (including .bam files); $1350 with interpretation (to yield STRs and SNPs).

    Time: 6-8 weeks for data to be analyzed
    Total time from order: about 12 weeks (in the pilot phase).

    Samples are collected via standard saliva sample collection kits and then analyzed via BGI in Hong Kong.

    Emails may be sent to this address (temporarily):
    justingenealogy11@gmail.com

    (typo corrected)
    Last edited by warwick; 03-25-2013 at 02:31 PM.

  2. The Following 5 Users Say Thank You to warwick For This Useful Post:

     Шад (04-12-2013), amerinese (05-18-2013), Clinton P (05-16-2013), Humanist (03-30-2013), rms2 (05-25-2013)

  3. #2
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    Note that the value of this effort comes with several individuals at specific y-tree branch points participate. This allows any new y-SNPs to be localized to sections of the y-tree.

  4. #3
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    Hello!

    Thanks for your interesting post. Bit of a newcomer here. I would like to understand what sort of deal this is, relative to getting testing done at some other lab, such as FTDNA.

    For example, how much would need to be spent to get an equivalent test made at FTDNA?
    Is the beta test described above even available at other labs?
    What would be a nice test to do after this test, to get data on mitochondrial and autosomal DNA?

    Thank you!

  5. #4
    Justin, I haven't seen you post this elsewhere. Is that deliberate, to avoid being overwhelmed with queries?

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    Quote Originally Posted by Ann Turner View Post
    Justin, I haven't seen you post this elsewhere. Is that deliberate, to avoid being overwhelmed with queries?
    Yes, though at the current price I don't think we'll be overwhelmed, plus qc has to be done as we proceed.

  7. #6
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    Quote Originally Posted by introvert View Post
    Hello!

    Thanks for your interesting post. Bit of a newcomer here. I would like to understand what sort of deal this is, relative to getting testing done at some other lab, such as FTDNA.

    For example, how much would need to be spent to get an equivalent test made at FTDNA?
    Is the beta test described above even available at other labs?
    What would be a nice test to do after this test, to get data on mitochondrial and autosomal DNA?

    Thank you!
    "equivalent test made at FTDNA?"
    There is no full Y chromosome test at FTDNA.

    "beta test described above even available at other labs?"

    Not to my knowledge.

    "autosomal DNA?"

    A microarray test for autosomal data is relatively straightforward to do.

  8. #7
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    Quote Originally Posted by warwick View Post
    Hello,

    I'm doing a Phase III pilot of our Y Chromosome sequencing via my organization, Full Genomes, Inc. (Per the prior approval of admins I'm announcing it here). We can take a limited number of additional orders as we get going:

    You receive:

    1. Full Y chromosome sequence
    2. 400-600 STRs
    3. 9000 snps-------------> correction > 1000 SNPs
    4. 14 gigabytes of data
    5. the full mtdna sequence can also be produced though we are doing quality control on this in the beta phase

    Cost: (not cheap) $1250 raw data (including .bam files); $1350 with interpretation (to yield STRs and SNPs).

    Time: 6-8 weeks for data to be analyzed
    Total time from order: about 12 weeks (in the pilot phase).

    Samples are collected via standard saliva sample collection kits and then sequenced via external collaborators..

    Emails may be sent to this address (temporarily):
    justingenealogy11@gmail.com

    (typo corrected)
    Corrections above.

  9. #8
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    Quote Originally Posted by warwick View Post
    3. 9000 snps
    4. 14 gigabytes of data
    How come you get only 9000 SNP and as much as 14 GB of data? You can store info about 9000 SNP far more efficiently...

  10. #9
    Senior Member Clinton P's Avatar
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    Quote Originally Posted by AndersP View Post
    How come you get only 9000 SNP and as much as 14 GB of data? You can store info about 9000 SNP far more efficiently...
    See here for full details.

    Clinton P
    Last edited by Clinton P; 05-02-2013 at 01:22 PM.
    • FullGenomes ID:FG1048A
    • YFull ID:YF01371


    y-DNA.................................................. ..........................mt-DNA
    Hg: R1b1a1a1a1b3 [R-U106 > FGC3861 > L217]........Hg: H2a2b [RSRS]
    Shorthand: R-L217 or R-S1849......................................Extra Mutations: 309.1'C', 315.1'C', A16235'G', T16357'C', C16519'T'.

    ySearch & mtSearch ID: R464G

  11. #10
    Senior Member MJost's Avatar
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    UnitedStatesofAmerica Netherlands IsleofMan Scotland Poland
    For the introductory price, are we to assume that this price includes an interpretation (to yield STRs and SNPs)?

    MJost
    f148326, FGC-0FW1R, YSeq-ID6. R-DF13>FGC5496>*5521>*5539>*5538>*5508>*5524
     
    Watterson USA GD1/67 & GD3/111, *5508+. GD1’s father’s sister-23andme pred. 3rd Cous w/ 0.91% DNA shared-3 seg. Largest on Chr1 w/non-Euro admix affirms my NPE paternal Watterson line via aDNA & YDNA. A 2nd pred. 4th cous has same DKA b. 1840's Georgia and MDKA d 1703 IOM. 3rd Cousin FtDNA FF appears to be from the same Watterson line via Ala. *5538+ b. IOM w/ GD6/67 & GD8/111 -SGD3. FGC5539+ a Scot-Ross GD13/111 -SGD8

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