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Thread: New DNA Papers

  1. #881
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    https://www.nature.com/articles/s41598-017-16271-y

    Article | Open

    Whole Y-chromosome sequences reveal an extremely recent origin of the most common North African paternal lineage E-M183 (M81)

    Neus Solé-Morata, Carla García-Fernández, Vadim Urasin, Asmahan Bekada, Karima Fadhlaoui-Zid, Pierre Zalloua, David Comas & Francesc Calafell

    Scientific Reports 7, Article number: 15941 (2017)
    doi:10.1038/s41598-017-16271-y

    Received: 10 May 2017
    Accepted: 09 November 2017
    Published online: 21 November 2017

    Abstract

    E-M183 (E-M81) is the most frequent paternal lineage in North Africa and thus it must be considered to explore past historical and demographical processes. Here, by using whole Y chromosome sequences from 32 North African individuals, we have identified five new branches within E-M183. The validation of these variants in more than 200 North African samples, from which we also have information of 13 Y-STRs, has revealed a strong resemblance among E-M183 Y-STR haplotypes that pointed to a rapid expansion of this haplogroup. Moreover, for the first time, by using both SNP and STR data, we have provided updated estimates of the times-to-the-most-recent-common-ancestor (TMRCA) for E-M183, which evidenced an extremely recent origin of this haplogroup (2,000–3,000 ya). Our results also showed a lack of population structure within the E-M183 branch, which could be explained by the recent and rapid expansion of this haplogroup. In spite of a reduction in STR heterozygosity towards the West, which would point to an origin in the Near East, ancient DNA evidence together with our TMRCA estimates point to a local origin of E-M183 in NW Africa.

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  3. #882
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    Mostly Dutch
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    R1b-U152 (prob. L2-)
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    W5

    Netherlands
    Quote Originally Posted by rozenfeld View Post

    Whole Y-chromosome sequences reveal an extremely recent origin of the most common North African paternal lineage E-M183 (M81)
    Expansion in Carthaginian times? Would be interesting.
    Ancestry (approx.):
    3/4 Dutch; 1/8 German+Belgian+French+English+Swiss; 1/16 Indonesian+Dutch Colonial; 3/64 Ashkenazi; 1/64 Sephardi.

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  5. #883
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    http://onlinelibrary.wiley.com/doi/1...23324/abstract

    Genetic diversity in Svaneti and its implications for the human settlement of the Highland Caucasus

    Yardumian A1,2, Shengelia R3, Chitanava D4, Laliashvili S4, Bitadze L4, Laliashvili I4, Villanea F5, Sanders A2, Azzam A2, Groner V2, Edleson K2, Vilar MG2,5, Schurr TG2.

    First published: 27 October 2017

    DOI: 10.1002/ajpa.23324

    Abstract

    Objectives

    In this study, we characterized genetic diversity in the Svans from northwestern Georgia to better understand the phylogeography of their genetic lineages, determine whether genetic diversity in the highland South Caucasus has been shaped by language or geography, and assess whether Svan genetic diversity was structured by regional residence patterns.

    Materials and Methods

    We analyzed mtDNA and Y-chromosome variation in 184 individuals from 13 village districts and townlets located throughout the region. For all individuals, we analyzed mtDNA diversity through control region sequencing, and, for males, we analyzed Y-chromosome diversity through SNP and STR genotyping. The resulting data were compared with those for populations from the Caucasus and Middle East.

    Results

    We observed significant mtDNA heterogeneity in Svans, with haplogroups U1-U7, H, K, and W6 being common there. By contrast, ∼78% of Svan males belonged to haplogroup G2a, with the remainder falling into four other haplogroups (J2a1, I2, N, and R1a). While showing a distinct genetic profile, Svans also clustered with Caucasus populations speaking languages from different families, suggesting a deep common ancestry for all of them. The mtDNA data were not structured by geography or linguistic affiliation, whereas the NRY data were influenced only by geography.

    Discussion

    These patterns of genetic variation confirm a complex set of geographic sources and settlement phases for the Caucasus highlands. Such patterns may also reflect social and cultural practices in the region. The high frequency and antiquity of Y-chromosome haplogroup G2a in this region further points to its emergence there.

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